By R T Blickenstaff
Antitumor Steroids examines using steroids, besides nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the therapy of melanoma. It explains the mechanism through which steroids and their receptors interact to impact their physiological features as a rule and their antitumor job specifically. It additionally describes the systematic screening of antitumor compounds remoted from usual assets.
Organized into 9 chapters, this ebook starts with an outline of the position of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters examine androgens, a few antiandrogens, derivatives according to C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl crew. The ebook explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of certainly taking place corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The publication concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This publication is a helpful source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating melanoma.
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Antitumor Steroids by R T Blickenstaff